Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages[S]

Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages[S]

Hydrolysis of intracellular cholesteryl ester (CE) is the rate-limiting step in the efflux of cholesterol from macrophage foam cells. In mouse peritoneal macrophages (MPMs), this process is thought to involve several enzymes: hormone-sensitive lipase (Lipe), carboxylesterase 3 (Ces3), neutral CE hyd...

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Bibliographic Details
Main Authors: Kent Sakai, Masaki Igarashi, Daisuke Yamamuro, Taichi Ohshiro, Shuichi Nagashima, Manabu Takahashi, Bolormaa Enkhtuvshin, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Shun Ishibashi
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Journal of Lipid Research
Subjects:
hormone-sensitive lipase
inhibitor
foam cells
efflux
paraoxon
lipoproteins
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520350070

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http://www.sciencedirect.com/science/article/pii/S0022227520350070

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