Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.

Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.

Acute Lung Injury (ALI) is a syndrome with high associated mortality characterized by severe hypoxemia and pulmonary infiltrates in patients with critical illness. We conducted the first investigation to use the genome wide association (GWA) approach to identify putative risk variants for ALI. Genom...

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Bibliographic Details
Main Authors: Jason D Christie, Mark M Wurfel, Rui Feng, Grant E O'Keefe, Jonathan Bradfield, Lorraine B Ware, David C Christiani, Carolyn S Calfee, Mitchell J Cohen, Michael Matthay, Nuala J Meyer, Cecilia Kim, Mingyao Li, Joshua Akey, Kathleen C Barnes, Jonathan Sevransky, Paul N Lanken, Addison K May, Richard Aplenc, James P Maloney, Hakon Hakonarson, Trauma ALI SNP Consortium (TASC) investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266233?pdf=render

Internet

http://europepmc.org/articles/PMC3266233?pdf=render

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