AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells

AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells

Abstract The study of primary glucagon-secreting α-cells is hampered by their low abundance and scattered distribution in rodent pancreatic islets. We have designed a double-stranded adeno-associated virus containing a rat proglucagon promoter (700 bp) driving enhanced green fluorescent protein (AAV...

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Bibliographic Details
Main Authors: Eva Tudurí, Maria M. Glavas, Ali Asadi, Robert K. Baker, Cara E. Ellis, Galina Soukhatcheva, Marjolaine Philit, Frank K. Huynh, James D. Johnson, C. Bruce Verchere, Timothy J. Kieffer
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46735-2

Internet

https://doi.org/10.1038/s41598-019-46735-2

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