E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of <span style="font-variant: small-caps">l</span>-Ascorbic Acid in a Rat Sciatic Nerve Model

E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of <span style="font-variant: small-caps">l</span>-Ascorbic Acid in a Rat Sciatic Nerve Model

Perineural adhesions leading to neuropathy are one of the most undesirable consequences of peripheral nerve surgery. However, there are currently no widely used compounds with anti-adhesive effects in the field of peripheral nerve surgery. E8002 is a novel, anti-adhesive, multi-layer membrane that c...

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Bibliographic Details
Main Authors: Kiyoshi Kikuchi, Kentaro Setoyama, Seiya Takada, Shotaro Otsuka, Kazuki Nakanishi, Kosuke Norimatsu, Akira Tani, Harutoshi Sakakima, Ko-ichi Kawahara, Kazuya Hosokawa, Ryoji Kiyama, Megumi Sumizono, Salunya Tancharoen, Ikuro Maruyama, Gohsuke Hattori, Motohiro Morioka, Eiichiro Tanaka, Hisaaki Uchikado
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
peripheral nerve adhesion
anti-adhesive membrane
E8002
<span style="font-variant: small-caps">l</span>-ascorbic acid
antioxidant
Online Access:https://www.mdpi.com/1422-0067/21/11/3972

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https://www.mdpi.com/1422-0067/21/11/3972

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