A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies
Faster, higher throughput antibody engineering methods are needed. Here the authors present CeVICA, a cell-free nanobody engineering platform using ribosome display and computational clustering analysis for in vitro selection; they use this to develop nanobodies against the RBD of SARS-CoV-2 spike p...
Main Authors: | Xun Chen, Matteo Gentili, Nir Hacohen, Aviv Regev |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25777-z |
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