Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

The epigenomic regulation of transcriptional programs in metastatic prostate cancer is poorly understood. We studied the epigenomic landscape of prostate cancer drivers using transcriptional profiling and ChIP‐seq in four clonal metastatic tumors derived from a single prostate cancer patient. Our ep...

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Bibliographic Details
Main Authors: Tesa M. Severson, Yanyun Zhu, Angelo M. De Marzo, Tracy Jones, Jonathan W. Simons, William G. Nelson, Srinivasan Yegnasubramanian, Matthew L. Freedman, Lodewyk Wessels, Andries M. Bergman, Michael C. Haffner, Wilbert Zwart
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Molecular Oncology
Subjects:
ChIP‐seq
cistrome
epigenomics
metastasis
prostate cancer
transcriptomics
Online Access:https://doi.org/10.1002/1878-0261.12923

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