Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.

by Brent A Orr, Michael C Haffner, William G Nelson, Srinivasan Yegnasubramanian, Charles G Eberhart
Published 2012-01-01

Putative Autoantigen Leiomodin-1 Is Expressed in the Human Brain and in the Membrane Fraction of Newly Formed Neurons

by David W. Nauen, Michael C. Haffner, Juyun Kim, Qizhi Zheng, Hao Yin, Angelo M. DeMarzo, Vasiliki Machairaki, Carlo Colantuoni, J. Geoffrey Pickering, Tory P. Johnson
Published 2020-12-01

If this is true, what does it imply? How end-user antibody validation facilitates insights into biology and disease

by Karen S. Sfanos, Srinivasan Yegnasubramanian, William G. Nelson, Tamara L. Lotan, Ibrahim Kulac, Jessica L. Hicks, Qizhi Zheng, Charles J. Bieberich, Michael C. Haffner, Angelo M. De Marzo
Published 2019-01-01

Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies.

by Enrico Munari, Alcides Chaux, Ajay M Vaghasia, Diana Taheri, Sarah Karram, Stephania M Bezerra, Nilda Gonzalez Roibon, William G Nelson, Srinivasan Yegnasubramanian, George J Netto, Michael C Haffner
Published 2016-01-01

A Comprehensive Analysis of FUT8 Overexpressing Prostate Cancer Cells Reveals the Role of EGFR in Castration Resistance

by Naseruddin Höti, Tung-Shing Lih, Jianbo Pan, Yangying Zhou, Ganglong Yang, Ashely Deng, Lijun Chen, Mingmimg Dong, Ruey-Bing Yang, Cheng-Fen Tu, Michael C. Haffner, Qing Kay Li, Hui Zhang
Published 2020-02-01

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

by Tesa M. Severson, Yanyun Zhu, Angelo M. De Marzo, Tracy Jones, Jonathan W. Simons, William G. Nelson, Srinivasan Yegnasubramanian, Matthew L. Freedman, Lodewyk Wessels, Andries M. Bergman, Michael C. Haffner, Wilbert Zwart
Published 2021-07-01

CD38 is methylated in prostate cancer and regulates extracellular NAD+

by Jack Mottahedeh, Michael C. Haffner, Tristan R. Grogan, Takao Hashimoto, Preston D. Crowell, Himisha Beltran, Andrea Sboner, Rohan Bareja, David Esopi, William B. Isaacs, Srinivasan Yegnasubramanian, Matthew B. Rettig, David A. Elashoff, Elizabeth A. Platz, Angelo M. De Marzo, Michael A. Teitell, Andrew S. Goldstein
Published 2018-09-01

TGM4: an immunogenic prostate-restricted antigen

by Laura Crowley, Charles G Drake, Ran Reshef, Pawel Muranski, Aleksandar Obradovic, Timothy O’Donnell, Uri Laserson, Tiezheng Yuan, Emmanuel S Antonarakis, Zoila A Lopez-Bujanda, Thomas R Nirschl, Rodney Macedo, Alexandros Papachristodoulou, Jelani C Zarif, Mithil K Soni, Michael C Haffner, H Benjamin Larman, Michael M Shen
Published 2021-06-01

Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

by W. Nathaniel Brennen, Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel, Brian Hanratty, Roshan Chikarmane, Alan K. Meeker, S. Lilly Zheng, Jody E. Hooper, Jun Luo, Angelo M. De Marzo, Eva Corey, Jianfeng Xu, Srinivasan Yegnasubramanian, Michael C. Haffner, Peter S. Nelson, William G. Nelson, William B. Isaacs, John T. Isaacs
Published 2021-04-01

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination

by Michael C. Haffner, David M. Esopi, Alcides Chaux, Meltem Gürel, Susmita Ghosh, Ajay M. Vaghasia, Harrison Tsai, Kunhwa Kim, Nicole Castagna, Hong Lam, Jessica Hicks, Nicolas Wyhs, Debika Biswal Shinohara, Paula J. Hurley, Brian W. Simons, Edward M. Schaeffer, Tamara L. Lotan, William B. Isaacs, George J. Netto, Angelo M. De Marzo, William G. Nelson, Steven S. An, Srinivasan Yegnasubramanian
Published 2017-07-01

Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma

by Gary L. Gallia, Ming Zhang, Yi Ning, Michael C. Haffner, Denise Batista, Zev A. Binder, Justin A. Bishop, Christine L. Hann, Ralph H. Hruban, Masaru Ishii, Alison P. Klein, Douglas D. Reh, Lisa M. Rooper, Vafi Salmasi, Rafael J. Tamargo, Qing Wang, Tara Williamson, Tianna Zhao, Ying Zou, Alan K. Meeker, Nishant Agrawal, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Chetan Bettegowda
Published 2018-12-01

Convergent network effects along the axis of gene expression during prostate cancer progression

by Konstantina Charmpi, Tiannan Guo, Qing Zhong, Ulrich Wagner, Rui Sun, Nora C. Toussaint, Christine E. Fritz, Chunhui Yuan, Hao Chen, Niels J. Rupp, Ailsa Christiansen, Dorothea Rutishauser, Jan H. Rüschoff, Christian Fankhauser, Karim Saba, Cedric Poyet, Thomas Hermanns, Kathrin Oehl, Ariane L. Moore, Christian Beisel, Laurence Calzone, Loredana Martignetti, Qiushi Zhang, Yi Zhu, María Rodríguez Martínez, Matteo Manica, Michael C. Haffner, Ruedi Aebersold, Peter J. Wild, Andreas Beyer
Published 2020-12-01

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

by Paloma Cejas, Yingtian Xie, Alba Font-Tello, Klothilda Lim, Sudeepa Syamala, Xintao Qiu, Alok K. Tewari, Neel Shah, Holly M. Nguyen, Radhika A. Patel, Lisha Brown, Ilsa Coleman, Wenzel M. Hackeng, Lodewijk Brosens, Koen M. A. Dreijerink, Leigh Ellis, Sarah Abou Alaiwi, Ji-Heui Seo, Sylvan Baca, Himisha Beltran, Francesca Khani, Mark Pomerantz, Alessandra Dall’Agnese, Jett Crowdis, Eliezer M. Van Allen, Joaquim Bellmunt, Colm Morrisey, Peter S. Nelson, James DeCaprio, Anna Farago, Nicholas Dyson, Benjamin Drapkin, X. Shirley Liu, Matthew Freedman, Michael C. Haffner, Eva Corey, Myles Brown, Henry W. Long
Published 2021-10-01