Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors

by Ekaterina Nevedomskaya, Lodewyk Wessels, Wilbert Zwart
Published 2014-12-01

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens.

by Jeroen de Ridder, Anthony Uren, Jaap Kool, Marcel Reinders, Lodewyk Wessels
Published 2006-12-01

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

by Christiaan Klijn, Jan Bot, David J Adams, Marcel Reinders, Lodewyk Wessels, Jos Jonkers
Published 2010-01-01

CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities

by Tomasz Ahrends, Julia Busselaar, Tesa M. Severson, Nikolina Bąbała, Evert de Vries, Astrid Bovens, Lodewyk Wessels, Fred van Leeuwen, Jannie Borst
Published 2019-12-01

Detection of Colorectal Cancer by Serum and Tissue Protein Profiling: A Prospective Study in a Population at Risk

by Judith Y.M.N. Engwegen, Annekatrien C.T.M. Depla, Annemieke Cats, Henriëtte Tuynman, Henk A. van Heukelem, Pleun Snel, Wouter Meuleman, Lodewyk Wessels, Jan H.M. Schellens, Jos H. Beijnen
Published 2008-01-01

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

by Mirjam C. Boelens, Micha Nethe, Sjoerd Klarenbeek, Julian R. de Ruiter, Eva Schut, Nicola Bonzanni, Amber L. Zeeman, Ellen Wientjens, Eline van der Burg, Lodewyk Wessels, Renée van Amerongen, Jos Jonkers
Published 2016-08-01

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

by Tesa M. Severson, Yanyun Zhu, Angelo M. De Marzo, Tracy Jones, Jonathan W. Simons, William G. Nelson, Srinivasan Yegnasubramanian, Matthew L. Freedman, Lodewyk Wessels, Andries M. Bergman, Michael C. Haffner, Wilbert Zwart
Published 2021-07-01

Parallel In Vivo and In Vitro Melanoma RNAi Dropout Screens Reveal Synthetic Lethality between Hypoxia and DNA Damage Response Inhibition

by Patricia A. Possik, Judith Müller, Carmen Gerlach, Juliana C.N. Kenski, Xinyao Huang, Aida Shahrabi, Oscar Krijgsman, Ji-Ying Song, Marjon A. Smit, Bram Gerritsen, Cor Lieftink, Kristel Kemper, Magali Michaut, Roderick L. Beijersbergen, Lodewyk Wessels, Ton N. Schumacher, Daniel S. Peeper
Published 2014-11-01

The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting

by Tesa M. Severson, Denise M. Wolf, Christina Yau, Justine Peeters, Diederik Wehkam, Philip C. Schouten, Suet-Feung Chin, Ian J. Majewski, Magali Michaut, Astrid Bosma, Bernard Pereira, Tycho Bismeijer, Lodewyk Wessels, Carlos Caldas, René Bernards, Iris M. Simon, Annuska M. Glas, Sabine Linn, Laura van ‘t Veer
Published 2017-08-01

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

by Tesa M. Severson, Yongsoo Kim, Stacey E. P. Joosten, Karianne Schuurman, Petra van der Groep, Cathy B. Moelans, Natalie D. ter Hoeve, Quirine F. Manson, John W. Martens, Carolien H. M. van Deurzen, Ellis Barbe, Ingrid Hedenfalk, Peter Bult, Vincent T. H. B. M. Smit, Sabine C. Linn, Paul J. van Diest, Lodewyk Wessels, Wilbert Zwart
Published 2018-02-01

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells

by Theodoros I. Roumeliotis, Steven P. Williams, Emanuel Gonçalves, Clara Alsinet, Martin Del Castillo Velasco-Herrera, Nanne Aben, Fatemeh Zamanzad Ghavidel, Magali Michaut, Michael Schubert, Stacey Price, James C. Wright, Lu Yu, Mi Yang, Rodrigo Dienstmann, Justin Guinney, Pedro Beltrao, Alvis Brazma, Mercedes Pardo, Oliver Stegle, David J. Adams, Lodewyk Wessels, Julio Saez-Rodriguez, Ultan McDermott, Jyoti S. Choudhary
Published 2017-08-01

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells

by Krishna Kalyan Kolluri, Constantine Alifrangis, Neelam Kumar, Yuki Ishii, Stacey Price, Magali Michaut, Steven Williams, Syd Barthorpe, Howard Lightfoot, Sara Busacca, Annabel Sharkey, Zhenqiang Yuan, Elizabeth K Sage, Sabarinath Vallath, John Le Quesne, David A Tice, Doraid Alrifai, Sylvia von Karstedt, Antonella Montinaro, Naomi Guppy, David A Waller, Apostolos Nakas, Robert Good, Alan Holmes, Henning Walczak, Dean A Fennell, Mathew Garnett, Francesco Iorio, Lodewyk Wessels, Ultan McDermott, Samuel M Janes
Published 2018-01-01