NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons

AgRP-expressing neurons regulate feeding, glucose homeostasis and locomotor activity, but the neurotransmitters that mediate these effects are unclear. Here the authors show that neuropeptide Y in these neurons regulates rapid feeding responses and insulin sensitivity, but not locomotor activity.

Bibliographic Details
Main Authors: Linda Engström Ruud, Mafalda M. A. Pereira, Alain J. de Solis, Henning Fenselau, Jens C. Brüning
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14291-3