Analysis of the mechanosensor channel functionality of TACAN

Mechanosensitive ion channels mediate transmembrane ion currents activated by mechanical forces. A mechanosensitive ion channel called TACAN was recently reported. We began to study TACAN with the intent to understand how it senses mechanical forces and functions as an ion channel. Using cellular pa...

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Bibliographic Details
Main Authors: Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/71188