KLF15 and PPARα Cooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation

The metabolic myocardium is an omnivore and utilizes various carbon substrates to meet its energetic demand. While the adult heart preferentially consumes fatty acids (FAs) over carbohydrates, myocardial fuel plasticity is essential for organismal survival. This metabolic plasticity governing fuel u...

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Bibliographic Details
Main Authors: Domenick A. Prosdocimo, Jenine E. John, Lilei Zhang, Elizabeth S. Efraim, Rongli Zhang, Xudong Liao, Mukesh K. Jain
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2015/201625