Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity

Objective: Sympathetic nervous system and immune cell interactions play key roles in the regulation of metabolism. For example, recent convergent studies have shown that macrophages regulate obesity through brown adipose tissue (BAT) activation and beiging of white adipose tissue (WAT) via effects u...

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Bibliographic Details
Main Authors: Marie-Therese Rached, Steven J. Millership, Silvia M.A. Pedroni, Agharul I. Choudhury, Ana S.H. Costa, Darran G. Hardy, Justyna A. Glegola, Elaine E. Irvine, Colin Selman, Megan C. Woodberry, Vijay K. Yadav, Sanjay Khadayate, Antonio Vidal-Puig, Samuel Virtue, Christian Frezza, Dominic J. Withers
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818310251