A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed. After heat shock, to which sexual but not asexual spores are highly resistant, the azole-free compost yielded 98% (49/50) wild...

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Bibliographic Details
Main Authors: Jianhua Zhang, Eveline Snelders, Bas J. Zwaan, Sijmen E. Schoustra, Jacques F. Meis, Karin van Dijk, Ferry Hagen, Martha T. van der Beek, Greetje A. Kampinga, Jan Zoll, Willem J. G. Melchers, Paul E. Verweij, Alfons J. M. Debets, Tom Chiller
Format: Article
Language:English
Published: American Society for Microbiology 2017-06-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/3/e00791-17

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http://mbio.asm.org/cgi/content/full/8/3/e00791-17

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