In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration

In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration

The mechanism and magnitude by which the mammalian kidney generates and maintains its proximal tubules, distal tubules, and collecting ducts remain controversial. Here, we use long-term in vivo genetic lineage tracing and clonal analysis of individual cells from kidneys undergoing development, maint...

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Bibliographic Details
Main Authors: Yuval Rinkevich, Daniel T. Montoro, Humberto Contreras-Trujillo, Orit Harari-Steinberg, Aaron M. Newman, Jonathan M. Tsai, Xinhong Lim, Renee Van-Amerongen, Angela Bowman, Michael Januszyk, Oren Pleniceanu, Roel Nusse, Michael T. Longaker, Irving L. Weissman, Benjamin Dekel
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714003052

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http://www.sciencedirect.com/science/article/pii/S2211124714003052

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