Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth
Runxiang Qiu et al find that conditional knockout of Kif20a, a regulator of cytokinesis and neural progenitor cell fate, induces early cell cycle exit and precocious neuronal differentiation of cerebellar granule neuron progenitors. They show that Kif20a depletion suppresses tumour formation in gene...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02075-4 |