Subtype differences in pre-coupling of muscarinic acetylcholine receptors.

Based on the kinetics of interaction between a receptor and G-protein, a myriad of possibilities may result. Two extreme cases are represented by: 1/Collision coupling, where an agonist binds to the free receptor and then the agonist-receptor complex "collides" with the free G-protein. 2/P...

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Bibliographic Details
Main Authors: Jan Jakubík, Helena Janíčková, Alena Randáková, Esam E El-Fakahany, Vladimír Doležal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3218020?pdf=render