Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein

α-Synuclein (αS) is an intrinsically disordered protein that is associated with Parkinson’s disease (PD) through its ability to self-assemble into oligomers and fibrils. Inhibition of this oligomerization cascade is an interesting approach to developing therapeutical strategies and β-synuclein (βS)...

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Bibliographic Details
Main Authors: Andre Leitao, Akshay Bhumkar, Dominic J. B. Hunter, Yann Gambin, Emma Sierecki
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/2/334