Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein
α-Synuclein (αS) is an intrinsically disordered protein that is associated with Parkinson’s disease (PD) through its ability to self-assemble into oligomers and fibrils. Inhibition of this oligomerization cascade is an interesting approach to developing therapeutical strategies and β-synuclein (βS)...
Main Authors: | Andre Leitao, Akshay Bhumkar, Dominic J. B. Hunter, Yann Gambin, Emma Sierecki |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/19/2/334 |
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