Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration.

Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration.

Parkinson disease (PD) involves progressive neurodegeneration, including loss of dopamine (DA) neurons from the substantia nigra. Select genes associated with rare familial forms of PD function in cellular pathways, such as the ubiquitin-proteasome system (UPS), involved in protein degradation. The...

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Bibliographic Details
Main Authors: Kim A Caldwell, Michelle L Tucci, Jafa Armagost, Tyler W Hodges, Jue Chen, Shermeen B Memon, Jeana E Blalock, Susan M DeLeon, Robert H Findlay, Qingmin Ruan, Philip J Webber, David G Standaert, Julie B Olson, Guy A Caldwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2751819?pdf=render

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http://europepmc.org/articles/PMC2751819?pdf=render

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