A neurotoxic phosphoform of Elk-1 associates with inclusions from multiple neurodegenerative diseases.

Neurodegenerative diseases are characterized by a number of features including the formation of inclusions, early synaptic degeneration and the selective loss of neurons. Molecules serving as links between these shared features have yet to be identified. Identifying candidates within the diseased mi...

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Bibliographic Details
Main Authors: Anup Sharma, Linda M Callahan, Jai-Yoon Sul, Tae Kyung Kim, Lindy Barrett, Minsun Kim, James M Powers, Howard Federoff, James Eberwine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2814869?pdf=render