Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders

Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders

The effector functions of T lymphocytes are responsible for most autoimmune disorders and act by directly damaging tissues or by indirectly promoting inflammation and antibody responses. Co-stimulatory and co-inhibitory T cell receptor molecules are the primary pharmacological targets that enable in...

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Bibliographic Details
Main Authors: Bernard Vanhove, Nicolas Poirier, Fadi Fakhouri, Laetitia Laurent, Bert ’t Hart, Pedro H. Papotto, Luiz V. Rizzo, Masaaki Zaitsu, Fadi Issa, Kathryn Wood, Jean-Paul Soulillou, Gilles Blancho
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Antibodies
Subjects:
autoimmunity
T cell costimulation
antibodies
Online Access:https://www.mdpi.com/2073-4468/6/4/19

Internet

https://www.mdpi.com/2073-4468/6/4/19

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