The use of comet assay to assess global DNA methylation in human biomonitoring studies.

The Comet assay is a valuable tool for the detection of DNA damage in genotoxicity and human biomonitoring studies. Throughout the years, this biomarker has undergone several adaptations in their protocol in order to increase its sensitivity and the possible outcomes. By including an additional step...

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Bibliographic Details
Main Authors: Carla Costa, Ana Catarina Alves
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/conf.fgene.2015.01.00015/full