Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis.

Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis.

Understanding the host immune response during cryptococcal meningitis (CM) is of critical importance for the development of immunomodulatory therapies. We profiled the cerebrospinal fluid (CSF) immune-response in ninety patients with HIV-associated CM, and examined associations between immune phenot...

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Bibliographic Details
Main Authors: Joseph N Jarvis, Graeme Meintjes, Tihana Bicanic, Viviana Buffa, Louise Hogan, Stephanie Mo, Gillian Tomlinson, Pascale Kropf, Mahdad Noursadeghi, Thomas S Harrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004754

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https://doi.org/10.1371/journal.ppat.1004754

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