Mitochondrial ROS and the effectors of the intrinsic apoptotic pathway in aging cells: the discerning killers!

It has become clear that mitochondrial reactive oxygen species (mtROS) are not simply villains and mitochondria the hapless targets of their attacks. Rather, it appears that mitochondrial dysfunction itself and the signaling function of mtROS can have positive effects on lifespan, helping to extend...

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Bibliographic Details
Main Authors: Siegfried Hekimi, Ying Wang, Alycia Noe
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00161/full