B Cells and B Cell Blasts Withstand Cryopreservation While Retaining Their Functionality for Producing Antibody

B Cells and B Cell Blasts Withstand Cryopreservation While Retaining Their Functionality for Producing Antibody

In individuals who have once developed humoral immunity to an infectious/foreign antigen, the antibodies present in their body can mediate instant protection when the antigen re-enters. Such antigen-specific antibodies can be readily detected in the serum. Long term humoral immunity is, however, als...

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Bibliographic Details
Main Authors: Philipp Fecher, Richard Caspell, Villian Naeem, Alexey Y. Karulin, Stefanie Kuerten, Paul V. Lehmann
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Cells
Subjects:
four color B cell ELISPOT
immune monitoring
freeze-thawing PBMC
plasma cells
antibody secretion
immunoglobulins
antibodies
immunoglobulin classes and subclasses
antibody-secreting cells
IgA
IgE
IgD
IgM
IgG1
IgG2
IgG3
IgG4
multiplex immune assay
Online Access:http://www.mdpi.com/2073-4409/7/6/50

Internet

http://www.mdpi.com/2073-4409/7/6/50

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