Analysis of Secondary Structure Biases in Naturally Presented HLA-I Ligands

Analysis of Secondary Structure Biases in Naturally Presented HLA-I Ligands

Recent clinical developments in antitumor immunotherapy involving T-cell related therapeutics have led to a renewed interest for human leukocyte antigen class I (HLA-I) binding peptides, given their potential use as peptide vaccines. Databases of HLA-I binding peptides hold therefore information on...

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Bibliographic Details
Main Authors: Marta A. S. Perez, Michal Bassani-Sternberg, George Coukos, David Gfeller, Vincent Zoete
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
human leukocyte antigen
HLA-I ligand presentation
computational immunology
3D structure
heuristic search
HLA-I motif-like peptides
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02731/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02731/full

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