The Regulation of Human β-Defensin 2 by the ETS Transcription Factor MEF (Myeloid Elf-1-Like Factor) Is Enhanced by Promyelocytic Leukemia Protein

The Regulation of Human β-Defensin 2 by the ETS Transcription Factor MEF (Myeloid Elf-1-Like Factor) Is Enhanced by Promyelocytic Leukemia Protein

The human β-defensin 2 (HBD 2) is a potent anti-bacterial peptide with a wide spectrum of activity. MEF (myeloid elf-1-like factor) or Elf4, a member of the ETS transcription factor family, has been shown to up-regulate the basal expression of the HBD 2 gene in epithelial cells. The mammalian cell n...

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Bibliographic Details
Main Authors: Mary Ann Suico, Zhuo Lu, Tsuyoshi Shuto, Tomoaki Koga, Tomoko Uchikawa, Hiroki Yoshida, Kazuhito Matsuzaki, Mitsuyoshi Nakao, Jian-Dong Li, Hirofumi Kai
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319323953

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http://www.sciencedirect.com/science/article/pii/S1347861319323953

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