Characterization of viral insulins reveals white adipose tissue-specific effects in mice

Characterization of viral insulins reveals white adipose tissue-specific effects in mice

Objective: Members of the insulin/insulin-like growth factor (IGF) superfamily are well conserved across the evolutionary tree. We recently showed that four viruses in the Iridoviridae family possess genes that encode proteins highly homologous to human insulin/IGF-1. Using chemically synthesized si...

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Bibliographic Details
Main Authors: Martina Chrudinová, François Moreau, Hye Lim Noh, Terezie Páníková, Lenka Žáková, Randall H. Friedline, Francisco A. Valenzuela, Jason K. Kim, Jiří Jiráček, C. Ronald Kahn, Emrah Altindis
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Molecular Metabolism
Subjects:
VILPs
Viral insulin
Insulin
IGF-1
GLUT4
Adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301952

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http://www.sciencedirect.com/science/article/pii/S2212877820301952

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