A Drosophila Mitochondrial Complex I Deficiency Phenotype Array

A Drosophila Mitochondrial Complex I Deficiency Phenotype Array

Mitochondrial diseases are a group of rare life-threatening diseases often caused by defects in the oxidative phosphorylation system. No effective treatment is available for these disorders. Therapeutic development is hampered by the high heterogeneity in genetic, biochemical, and clinical spectra o...

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Bibliographic Details
Main Authors: Sarah Foriel, G. Herma Renkema, Yvonne Lasarzewski, Job Berkhout, Richard J. Rodenburg, Jan A. M. Smeitink, Julien Beyrath, Annette Schenck
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
mitochondrial disease
complex I deficiency
Drosophila melanogaster
disease model
screening
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00245/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00245/full

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