Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity

Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity

While tuberculosis continues to afflict mankind, the immunological mechanisms underlying TB disease development are still incompletely understood. Advanced preclinical models for TB research include both rhesus and cynomolgus macaques (Macaca mulatta and Macaca fascicularis, respectively), with rhes...

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Bibliographic Details
Main Authors: Karin Dijkman, Richard A. W. Vervenne, Claudia C. Sombroek, Charelle Boot, Sam O. Hofman, Krista E. van Meijgaarden, Tom H. M. Ottenhoff, Clemens H. M. Kocken, Krista G. Haanstra, Michel P. M. Vierboom, Frank A. W. Verreck
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
innate immunity
non-human primates
pulmonary immunology
experimental models of disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02479/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02479/full

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