Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

Four serine/threonine kinases are present in all mycobacteria: PknA, PknB, PknG and PknL. PknA and PknB are essential for growth and replication, PknG regulates metabolism, but little is known about PknL. Inactivation of pknL and adjacent regulator MSMEG_4242 in rough colony M. smegmatis mc2155 prod...

Full description

Bibliographic Details
Main Authors: Estalina Báez-Ramírez, Luis Querales, Carlos Andres Aranaga, Gustavo López, Elba Guerrero, Laurent Kremer, Séverine Carrère-Kremer, Albertus Viljoen, Mamadou Daffé, Françoise Laval, Stewart T. Cole, Andrej Benjak, Pedro Alzari, Gwenaëlle André-Leroux, William R. Jacobs, Jr., Catherine Vilcheze, Howard E. Takiff
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:The Cell Surface
Subjects:
Tuberculosis
Kinase
PknL
Lsr2
Biofilms
Mycobacterial envelope
Online Access:http://www.sciencedirect.com/science/article/pii/S246823302100013X

Internet

http://www.sciencedirect.com/science/article/pii/S246823302100013X

Similar Items