Phylogenetic and functional assessment of orthologs inference projects and methods.

Accurate genome-wide identification of orthologs is a central problem in comparative genomics, a fact reflected by the numerous orthology identification projects developed in recent years. However, only a few reports have compared their accuracy, and indeed, several recent efforts have not yet been...

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Bibliographic Details
Main Authors: Adrian M Altenhoff, Christophe Dessimoz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2612752?pdf=render