Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children

Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children

Down syndrome (DS) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans, which results from the triplication of chromosome 21. To search for biomarkers for the early detection and exploration of the disease mechanisms, here, we investigated the p...

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Bibliographic Details
Main Authors: Chiara Lanzillotta, Viviana Greco, Diletta Valentini, Alberto Villani, Valentina Folgiero, Matteo Caforio, Franco Locatelli, Sara Pagnotta, Eugenio Barone, Andrea Urbani, Fabio Di Domenico, Marzia Perluigi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
proteomics
Down syndrome
peripheral blood mononuclear cells (PBMCs)
unfolded protein response
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/9/11/1112

Internet

https://www.mdpi.com/2076-3921/9/11/1112

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