Genomic analysis of DNA repair genes and androgen signaling in prostate cancer

Genomic analysis of DNA repair genes and androgen signaling in prostate cancer

Abstract Background The cellular effects of androgen are transduced through the androgen receptor, which controls the expression of genes that regulate biosynthetic processes, cell growth, and metabolism. Androgen signaling also impacts DNA damage signaling through mechanisms involving gene expressi...

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Bibliographic Details
Main Authors: Kasey Jividen, Katarzyna Z Kedzierska, Chun-Song Yang, Karol Szlachta, Aakrosh Ratan, Bryce M Paschal
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Prostate cancer
Androgen receptor
DNA repair and DNA damage response
Online Access:http://link.springer.com/article/10.1186/s12885-018-4848-x

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http://link.springer.com/article/10.1186/s12885-018-4848-x

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