Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree

Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree

To study disease development, an inventory of an organ's cell types and understanding of physiologic function is paramount. Here, we performed single-cell RNA-sequencing to examine heterogeneity of murine pancreatic duct cells, pancreatobiliary cells, and intrapancreatic bile duct cells. We des...

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Bibliographic Details
Main Authors: Audrey M Hendley, Arjun A Rao, Laura Leonhardt, Sudipta Ashe, Jennifer A Smith, Simone Giacometti, Xianlu L Peng, Honglin Jiang, David I Berrios, Mathias Pawlak, Lucia Y Li, Jonghyun Lee, Eric A Collisson, Mark S Anderson, Gabriela K Fragiadakis, Jen Jen Yeh, Chun Jimmie Ye, Grace E Kim, Valerie M Weaver, Matthias Hebrok
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
scRNA-seq
pancreatic duct ligation
Osteopontin
Geminin
duct heterogeneity
Online Access:https://elifesciences.org/articles/67776

Internet

https://elifesciences.org/articles/67776

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