RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications

The human nasal epithelium is the primary site of exposure to influenza virus, the initiator of host responses to influenza and the resultant pathologies. Influenza virus may cause serious respiratory infection resulting in major complications, as well as severe impairment of the airways. Here, we e...

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Bibliographic Details
Main Authors: Kai Sen Tan, Anand Kumar Andiappan, Bernett Lee, Yan Yan, Jing Liu, See Aik Tang, Josephine Lum, Ting Ting He, Yew Kwang Ong, Mark Thong, Hui Fang Lim, Hyung Won Choi, Olaf Rotzschke, Vincent T Chow, De Yun Wang
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
influenza
H3N2 virus
human nasal epithelial cells (hNECs)
RNA sequencing
transcriptomics
epithelial responses
pathogenesis
Online Access:https://www.mdpi.com/2073-4409/8/9/986

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https://www.mdpi.com/2073-4409/8/9/986

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