DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells

DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells

Helminths like Schistosoma mansoni release excretory/secretory (E/S) products that modulate host immunity to enable infection. Extracellular vesicles (EVs) are among these E/S products, yet molecular mechanisms and functionality of S. mansoni EV interaction with host immune cells is unknown. Here we...

Full description

Bibliographic Details
Main Authors: Marije E. Kuipers, Esther N.M. Nolte-‘t Hoen, Alwin J. van der Ham, Arifa Ozir-Fazalalikhan, D. Linh Nguyen, Clarize M. de Korne, Roman I. Koning, John J. Tomes, Karl F. Hoffmann, Hermelijn H. Smits, Cornelis H. Hokke
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
schistosoma mansoni
glycans
dc-sign
immune responses
Online Access:http://dx.doi.org/10.1080/20013078.2020.1753420

Internet

http://dx.doi.org/10.1080/20013078.2020.1753420

Similar Items