NOS induction by NGF in basal forebrain cholinergic neurones: evidence for regulation of brain NOS by a neurotrophin

NOS induction by NGF in basal forebrain cholinergic neurones: evidence for regulation of brain NOS by a neurotrophin

Nerve growth factor (NGF) acts through trkA receptors to serve as a trophic factor for cholinergic neurones in the medial septal nucleus (MSN) and vertical limb of the diagonal band (VDB). Herein, we show that brain nitric oxide synthase (NOS), which synthesizes the neuromodulator nitric oxide, is s...

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Bibliographic Details
Main Authors: David M. Holtzman, Joshua Kilbridge, David S. Bredt, Stephen M. Black, Yiwen Li, Douglas O. Clary, Louis F. Reichardt, William C. Mobley
Format: Article
Language:English
Published: Elsevier 1994-11-01
Series:Neurobiology of Disease
Subjects:
basal forebrain cholinergic neurones
nerve growth factor
neurotrophic factor
neurotrophin
nitric oxide synthase
trkA
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996184700076

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http://www.sciencedirect.com/science/article/pii/S0969996184700076

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