Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma

Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma

Cancer-derived extracellular vesicles (EVs) are membrane-enclosed structures of highly variable size. EVs contain a myriad of substances (proteins, lipid, RNA, DNA) that provide a reservoir of circulating molecules, thus offering a good source of biomarkers. We demonstrate here that large EVs (L-EV)...

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Bibliographic Details
Main Authors: Tatyana Vagner, Cristiana Spinelli, Valentina R. Minciacchi, Leonora Balaj, Mandana Zandian, Andrew Conley, Andries Zijlstra, Michael R. Freeman, Francesca Demichelis, Subhajyoti De, Edwin M. Posadas, Hisashi Tanaka, Dolores Di Vizio
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Journal of Extracellular Vesicles
Subjects:
DNA
L-EVs
S-EVs
plasma
prostate cancer
liquid biopsy
Online Access:http://dx.doi.org/10.1080/20013078.2018.1505403

Internet

http://dx.doi.org/10.1080/20013078.2018.1505403

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