T cell receptor-like recognition of tumor in vivo by synthetic antibody fragment.

T cell receptor-like recognition of tumor in vivo by synthetic antibody fragment.

A major difficulty in treating cancer is the inability to differentiate between normal and tumor cells. The immune system differentiates tumor from normal cells by T cell receptor (TCR) binding of tumor-associated peptides bound to Major Histocompatibility Complex (pMHC) molecules. The peptides, der...

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Bibliographic Details
Main Authors: Keith R Miller, Akiko Koide, Brenda Leung, Jonathan Fitzsimmons, Bryan Yoder, Hong Yuan, Michael Jay, Sachdev S Sidhu, Shohei Koide, Edward J Collins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22916301/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22916301/pdf/?tool=EBI

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