Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1.

Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1.

The dietary fiber guar gum has beneficial effects on obesity, hyperglycemia and hypercholesterolemia in both humans and rodents. The major products of colonic fermentation of dietary fiber, the short-chain fatty acids (SCFAs), have been suggested to play an important role. Recently, we showed that S...

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Bibliographic Details
Main Authors: Gijs den Besten, Albert Gerding, Theo H van Dijk, Jolita Ciapaite, Aycha Bleeker, Karen van Eunen, Rick Havinga, Albert K Groen, Dirk-Jan Reijngoud, Barbara M Bakker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546369?pdf=render

Internet

http://europepmc.org/articles/PMC4546369?pdf=render

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