CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients.

BACKGROUND:Neuroblastoma is a pediatric cancer that exhibits a wide clinical spectrum ranging from spontaneous regression in low-risk patients to fatal disease in high-risk patients. The identification of single nucleotide polymorphisms (SNPs) may help explain the heterogeneity of neuroblastoma and...

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Main Authors: Ali Rihani, Bram De Wilde, Fjoralba Zeka, Geneviève Laureys, Nadine Francotte, Gian Paolo Tonini, Simona Coco, Rogier Versteeg, Rosa Noguera, Johannes H Schulte, Angelika Eggert, Raymond L Stallings, Frank Speleman, Jo Vandesompele, Tom Van Maerken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263607?pdf=render