The Reverse Warburg Effect Is Associated with Fbp2-Dependent Hif1α Regulation in Cancer Cells Stimulated by Fibroblasts

Fibroblasts are important contributors to cancer development. They create a tumor microenvironment and modulate our metabolism and treatment resistance. In the present paper, we demonstrate that healthy fibroblasts induce metabolic coupling with non-small cell lung cancer cells by down-regulating th...

Full description

Bibliographic Details
Main Authors: Przemysław Duda, Jakub Janczara, James A. McCubrey, Agnieszka Gizak, Dariusz Rakus
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/205