PPARγ controls Dectin-1 expression required for host antifungal defense against Candida albicans.

PPARγ controls Dectin-1 expression required for host antifungal defense against Candida albicans.

We recently showed that IL-13 or peroxisome proliferator activated receptor gamma (PPARgamma) ligands attenuate Candida albicans colonization of the gastrointestinal tract. Here, using a macrophage-specific Dectin-1 deficient mice model, we demonstrate that Dectin-1 is essential to control fungal ga...

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Bibliographic Details
Main Authors: Amandine Galès, Annabelle Conduché, José Bernad, Lise Lefevre, David Olagnier, Maryse Béraud, Guillaume Martin-Blondel, Marie-Denise Linas, Johan Auwerx, Agnès Coste, Bernard Pipy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20062524/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20062524/?tool=EBI

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