Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer’s Disease

Alzheimer′s disease (AD) is the most common age-related neurodegenerative disorder in which learning, memory and cognitive functions decline progressively. Familial forms of AD (FAD) are caused by mutations in amyloid precursor protein (<i>APP</i>), presenilin 1 (<i>PSEN1</i>...

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Bibliographic Details
Main Authors: Alice Rossi, Luisa Galla, Chiara Gomiero, Lorena Zentilin, Mauro Giacca, Valentina Giorgio, Tito Calì, Tullio Pozzan, Elisa Greotti, Paola Pizzo
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/204