Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy

Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy

Developing effective therapies for the treatment of advanced head-and-neck squamous cell carcinoma (HNSCC) remains a major challenge, and there is a limited landscape of effective targeted therapies on the horizon. NAD(P)H:quinone oxidoreductase 1 (NQO1) is a 2-electron reductase that is overexpress...

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Bibliographic Details
Main Authors: Alycen P. Lundberg, Matthew W. Boudreau, Kim A. Selting, Lindsay E. Chatkewitz, Jonathan Samuelson, Joshua M. Francis, Elizabeth I. Parkinson, Anne M. Barger, Paul J. Hergenrother, Timothy M. Fan
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Comparative oncology
NQO1
Targeted therapy
Feline
Preclinical
Online Access:http://www.sciencedirect.com/science/article/pii/S147655862100049X

Internet

http://www.sciencedirect.com/science/article/pii/S147655862100049X

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