Characterization of genomic variations in SNPs of PE_PGRS genes reveals deletions and insertions in extensively drug resistant (XDR) M. tuberculosis strains from Pakistan

Characterization of genomic variations in SNPs of PE_PGRS genes reveals deletions and insertions in extensively drug resistant (XDR) M. tuberculosis strains from Pakistan

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Background: Mycobacterium tuberculosis (MTB) PE_PGRS genes belong to the PE multigene family. Although the function of PE_PGRS genes is unknown, it is hypothesized that the PE_PGRS genes may be associated with antigenic variability in MTB. Material and methods: Whole genome sequencing analysis was p...

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Bibliographic Details
Main Authors: Akbar Kanji, Zahra Hasan, Asho Ali, Ruth McNerney, Kim Mallard, Francesc Coll, Grant Hill-Cawthorne, Mridul Nair, Taane G Clark, Ambreen Zaver, Sana Jafri, Rumina Hasan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:International Journal of Mycobacteriology
Subjects:
Whole genome sequencing
Mycobacterium tuberculosis
PE_PGRS genes
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=1;spage=73;epage=79;aulast=Kanji

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http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=1;spage=73;epage=79;aulast=Kanji

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