Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells

Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells

During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, their abnormality is associated with various brain...

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Bibliographic Details
Main Authors: Peiyan Ni, Haneul Noh, Zhicheng Shao, Qian Zhu, Youxin Guan, Joshua J. Park, Fatima Arif, James M. Park, Chiderah Abani, Cameron Beaudreault, Joy S. Park, Elizabeth Berry, Alexander Moghadam, Patric Stanton, John N. Hutchinson, Bill Andrews, Clare Faux, John Parnevelas, Leonard M. Eisenberg, Kyungjoon Park, Vadim Y. Bolshakov, Sangmi Chung
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050119300348

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http://www.sciencedirect.com/science/article/pii/S2329050119300348

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