Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells

Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells

To characterize susceptibility to HIV infection, we phenotyped infected tonsillar T cells by single-cell mass cytometry and created comprehensive maps to identify which subsets of CD4+ T cells support HIV fusion and productive infection. By comparing HIV-fused and HIV-infected cells through dimensio...

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Bibliographic Details
Main Authors: Marielle Cavrois, Trambak Banerjee, Gourab Mukherjee, Nandhini Raman, Rajaa Hussien, Brandon Aguilar Rodriguez, Joshua Vasquez, Matthew H. Spitzer, Nicole H. Lazarus, Jennifer J. Jones, Christina Ochsenbauer, Joseph M. McCune, Eugene C. Butcher, Ann M. Arvin, Nandini Sen, Warner C. Greene, Nadia R. Roan
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Cell Reports
Subjects:
HIV
CD4+ T cell
CyTOF
viral fusion
remodeling
CD127
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471730935X

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http://www.sciencedirect.com/science/article/pii/S221112471730935X

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