Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease

Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease

Abstract Background Clinical laboratory (lab) tests are used in clinical practice to diagnose, treat, and monitor disease conditions. Test results are stored in electronic health records (EHRs), and a growing number of EHRs are linked to patient DNA, offering unprecedented opportunities to query rel...

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Bibliographic Details
Main Authors: Jessica K. Dennis, Julia M. Sealock, Peter Straub, Younga H. Lee, Donald Hucks, Ky’Era Actkins, Annika Faucon, Yen-Chen Anne Feng, Tian Ge, Slavina B. Goleva, Maria Niarchou, Kritika Singh, Theodore Morley, Jordan W. Smoller, Douglas M. Ruderfer, Jonathan D. Mosley, Guanhua Chen, Lea K. Davis
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Genome Medicine
Subjects:
Electronic health records
Population genetics
Genetic epidemiology
Biomarkers
Online Access:https://doi.org/10.1186/s13073-020-00820-8

Internet

https://doi.org/10.1186/s13073-020-00820-8

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